Oncortarget publishes review articles on scientific research one of their resent publication is on the research work done by Wanxin tang on diabetic nephropathy which has affected a lot of patients and there has been little studies in that area. The pathogenesis of the disease is not well understood. This scientist suspected that the disease arises from the proximal tubular cells and that’s why they used RNA from that region. They suspected hat there has been strong relationship between the disease and the long non coding RNA. So he focused was on this RNA which he also knew is involved with regulating genes associated with diabetic nephropathy.
An experiment was carried out on from mouse kidney tubular cell whose RNA was sequenced. After sequencing of the RNA, followed the comparison of the sequence with those of human using BLAST software and from that they were able to identify of the gene also in humans just as in mice. These are the genes they suspected to the bio indicators for diabetic nephropathy that is lncRNA. This suggested that maybe lncRNA may be the biological indicator of diabetic nephropathy in humans too. Increased knowledge in these biomarkers provides new way on how this disease can be tackled at the gene level.
Oncotarget publishes journals which can be accessed for by anyone inorder create a suitable environment for scientific research. By providing free to access journals and publications in eradicates the barriers in the fight against diseases. Its purpose is to allow a biomedical research in an aim creating a disease free world. Oncotarget carries out publications on various topics such as microbiology and molecular genetics.
In order to eradicate diseases oncotarget has made an effort that all biomedical journals and scientific publications will continue to be published in pubmed , EMBASE,scopus and all other scientific journal websites and shall be published twice weekly. Through this they want to increase access to these journals to all these readers. By working with scientific indexes and also with scientific archives it ensures that journals are readily available and can be easily accessed by anyone. oncotarget ensure that all its papers remains on the published site permanent.